Beirut Oncology | Publications

2011

Larkin JM, Fisher RA, Pickering LM, Sohaib SA, *Ghosn M, Christmas T, Cordiner RL, Gore ME. Chromophobe Renal Cell Carcinoma With Prolonged Response to Sequential Sunitinib and Everolimus. J Clin Oncol. 2011 Jan 18. [Epub ahead of print].

2010

GHOSN M, BOUTROS C, GEARA S, KATTAN J, NASR F, CHAHINE G, Experience with palliative care in patients with advanced cancer at a tertiary care hospital in a developing country. Supportive Care Cancer 2010, Dec 18 [Epub ahead of print].

GHOSN M, AFTIMOS P, FARHAT FS, KATTAN JG, HANNA C, HADDAD N, NASR F, CHAHINE G, A phase II randomized study comparing navelbine and capecitabine (Navcap) followed either by Navcap or by weekly docetaxel in the first-line treatment of HER-2/neu negative metastatic breast cancer. Med Oncol 2010 Dec [Epub ahead of print].

AFTIMOS PG, NASR EA, NASR DI, NOUN RJ, NASR FL, GHOSN MG, EL HELOU JA, CHAHINE GY, Adjuvant chemo-radiation for gastric adenocarcinoma: an institutional experience. RadiatOncol. 2010 Jun 4; 5(1):50.

GHOSN MG, HADDAD AC, NASSAR MN, ABADJIAN GA, KARAK FR, AFTIMOS PG, Acute Myeloid Leukemia and Langerhans’ cell histiocytosis: Multiple theories for a usual presentation. Leuk Res. 2010 Mar;34(3):406-8.

FARHAT FS, KATTAN J, GHOSN MG, Role of capecitabine and irinotecan combination therapy in advanced or metastatic gastric cancer. Expert Rev Anticancer Ther. 2010 Apr; 10(4):541-8. Review.

FARHAT FS, KATTAN J, CHAHINE GY, YOUNES FC, NASR FL, MROUE RM, GHOSN MG, Role of low dose Capecitabine combined to Irinotecan in advanced and metastatic gastric cancer. Med Oncol. 2010 Sep;27(3):722-7.

2008

M. GHOSN, F. FARHAT, J. KATTAN, F. YOUNES, F. NASR, W. MOUKADEM, J. GASMI, G. CHAHINE, Sequential vinorelbine – capecitabine followed by docetaxel in advanced breast cancer: Long-term results of a pilot phase II trial. Cancer Chemotherapy & Pharmacology 2008, 62: 11-18.

Y. ABOU-MOURAD, Z. OTROCK, J. MAKAREM, J. KATTAN, F. FARHAT, R. JALLOUL, W. MOUKADDEM, M. GHOSN, A. TAHER, A. CHEHAL, A. SHAMSEDDINE, Docetaxel and Irinotecan as First-Line chemotherapy in patients with advanced non-small cell lung cancer: a pilot study. J Med Liban 2008: 56 (1): 16 – 21..

KATTAN J, NASR F, CHAHINE G, FARHAT F, MOUKADEM W, YOUNES F, YAZBECK N, M. GHOSN, Weekly Docetaxel, Zoledronic Acid and Estramustine in Hormone-Refractory Prostate Cancer Patients (HRPC). Investigational New Drugs 2008 Feb; 26 (1): 75 – 9.

2007

H. KANSO, H. KAZZI, S. ABI-KHALIL, M. GHOSN, G. CHAHINE, C TOHME, N AOUN and M. GHOSSAIN, Interest of systematic Ultrasound for the scar of mastectomy. Journal de Radiologie, Tome 88, October 2007.

M. GHOSN, F. FARHAT, J. KATTAN, F. YOUNES, W. MOUKADEM, F. NASR, G. CHAHINE, FOLFOX-6 combination as the first-line treatment of locally advanced and/or metastatic pancreatic cancer. Hotel-Dieu de France University Hospital, Beirut; Hammoud Hospital, Sidon; Haikal Hospital, Tripoli. For the Cancer Research Group/Collaborative Group, Beirut, Lebanon. American Journal of Clinical Oncology 2007, 30 (1): 15-20.

2006

M. GHOSN, J. KATTAN, F. FARHAT, F. YOUNES, J. GASMI, Phase II trial of Capecitabine and Vinorelbine as first line chemotherapy for metastatic breast cancer patients. Hôtel-Dieu de France University Hospital, Beirut, Lebanon; Hammoud University Hospital Medical Center, Sidon, Lebanon; Institut de Recherche Pierre Fabre, Boulogne, France. Original. Anticancer Research 2006, 26: 2451 – 6..

2005

E. NASR, S. MERHEJ, D. NASR, G. FARES, M. MOUKARZEL, E. CHALOUHI, M. BULBUL, P. SARKIS, E. NEMR, M. JABBOUR, R. KHOURY, G. GHAZALE, G. CHEHADE, M. GHOSN, G. CHAHINE, A. ABILLAMAH, A five-year experience in conformational radiotherapy in the treatment of a prostate cancer. Evaluation of acute toxicity in 131 patients. Progrès en Urologie 2005; 15 (1): 36 – 9. (Original).

2004

NASR F, CHAHINE G, KATTAN J, FARHAT F, TUEINI E, MOUKADEM W, DAGHER J, GHOSN M, Gemcitabine plus Carboplatinum (GC) Combination Therapy as Second Line Treatment in Relapsed Breast Cancer Patients. Clinical Breast Cancer 2004; 5 (2): 117-22. (Original).

SIBAI A, SHAMSUDDINE A, GEHCHAN N, RAHAL B, EL-SAGHIR N, GHOSN M, AFTIMOS G, CHAMSUDDINE N, SEOUD M, AUB MC Beirut, Lebanon, Cancer incidence in Postwar Lebanon: the first population-based estimates, 1993 and 1998. Annals of Epidemiology 2004; 14 (9): 663-8. (Original).

GHOSN M, KATTAN J, Weekly Chemotherapy in Metastatic Breast Cancer: the Ideamorphing (Quimioterapia seminal emcâncer de mama). Cancer Höje 2004; 2 (4):15-7. (article in Portuguese, review).

2003

CHALHOUB-HACHEM BR, KATTAN JG, GHOSN MG, ABADJIAN GA, OKAIS NM, Departments of Hematology-Oncology, Pathology and Neuro-surgery, Hôtel-Dieu de France University Hospital, Beirut, Lebanon. Granulocytic sarcoma with spinal cord compression in chronic myelogenous leukemia: a case report. Lebanese Medical Journal 2003; 51 (2): 117-9. (Case report).

2002

EL MURR T, TOHME A, GHOSN M, GHAYAD E, Pseudomyxomepéritonéal: A propos de deuxcas et revue de la littérature. Lebanese Medical Journal2002, 50 (4): 187-90. (Original).

GHOSN M, KANSO CH, KATTAN J. CHAHINE G, TUEINI, NASSER E, YAZBECK P, Outcome of Cancer Patients admitted to the intensive care unit (ICU). Lebanese Medical Journal, 50 (4): 132-7. (Original).

2001

EL MURR T, TOHME A, FARAH E, ABADJIAN G, GHOSN M, GHAYAD E, Vertebral actinomycosis: case report and review of the literature. Lebanese Medical Journal2001, 49 (6): 355-8. (Original).

KATTAN J, FARAJ H, GHOSN M, CHAHINE G, ASSAF E, ABADJIAN G, KHOURY F, Mesothelioma-Asbestos in Lebanon: a problem to be considered. Lebanese Medical Journal2001, 49 (6): 333 – 7. (Case /review).

ABOU CHACRA L, GHOSN M, GHAYAD E, HONEIN K., A case of pancreatitis associated with all-trans-retinoic acid therapy in acute promyelocytic leukemia. The Hematology Journal (Haematologica) 2001, 2: 406-7. (Case report).

1999

KATTAN J, GHOSN M, Chemoprevention of breast cancer. Impact of a new therapeutic strategy. Lebanese Medical Journal1999, 47 (5): 284 – 5. (Original).

1997

KATTAN J, GHOSN M. , Cancer in the elderly a special and unique entity. Lebanese Medical Journal 1997, 45 (3): 172 – 3. (Original).

1994

GHOSN M, KATTAN J, NASR F, Retinoids in Chimioprévention. Revue MédicaleLibanaise 1994, 6 (4): 242. (Original).

ABBOUD B, SAYEGH R, CHAHINE G, GHOSN M, INGEA H, BIAJINI J, FARAH P, MétastaseGastriques du cancer du sein. PresseMédicale 1994, 23(38): 1758 – 9. (Original).

GHOSN M, DAGHER E, NASR F, CHAHINE G, TALEB N, NASNAS R, GHAYAD E, Infections in cancer patients with granulocytopenia. Retrospective studies of 59 febrile episodes with hospitalization. Lebanese Medical Journal1994, 42 (3): 117 - 22. (Original).

MORAN-RIBON, J.P. DROZ, J. KATTAN, B. LECLERCQ, M. GHOSN, D. COUANET, M.OSTRONOFF, S. CULINE, B. MISSET, B. ESCUDIER, R. RUFFIE, G. NITENBERG, Super-high-risk germ-cell tumors: a clinical entity. Report of eleven cases. Supportive Care in Cancer 1994, 2: 253 - 8. (Report of 11 cases).

1993

GHOSN M, TALEB N, Compterendu de réunion : 1er Congrèsd’Oncologie du Moyen-Orient, Beyrouth, Liban, 7 - 10 Juillet 1993. Bulletin du Cancer 1994, 81: 157 – 9. (Meeting report)..

GHOSN M, GANNAGE M, Cancer Pain: Pharmocological Management (second of two parts). Lebanese Medical Journal1993, 42 (4): 244 – 8. (Original).

GHOSN M, GANNAGE M, Pain: Pharmacological Management (first of two parts. Lebanese Medical Journal1993, 41 (3): 174 – 6. (Original).

GHOSN M, CHOUEIFATY N, Greffe de MoëlleOsseuse :Allogreffe et Autogreffe. Le Monde Médical 1993, 10 (4): 29 - 44. (Original).

1992

AZOURI J, AFIF N, GHOSN M, NADER N, BOU SABA C, Primary breast lymphoma. A case report. Lebanese Medical Journal1992, 40 (4)²&: 202 - 6. (Original).

HABIB C, KARAM S, KHALED H, RUSTOM R, GUEUTCHERIAN Y, AKATCHERIAN R, GHOSN M, Handling of antineoplastic products and nurses’ Knowledge. Lebanese Medical Journal 1992, 40 (4): 182 - 6. (Original).

BIAGINI J, SAYEGH R, GHOSN M, Therapeutic problem posed by Gardner’s syndrome, report of a Lebanese family. Lebanese Medical Journal1992, 40 (4): 182-6. (Original).

GHOSN M, DROZ JP, The use of antiemetics in cancer chemotherapy. Lebanese Medical Journal1992, 40 (2): 93-5. (Original).

MAHJOUBI M, KATTAN J, GHOSN M, DROZ J.P, PHILIPPOT I, HERAIT P, Phase II trial of pirarubicin in the treatment of advanced bladder cancer. Invest New Drugs 1992, 10 (4): 317 – 21. (Original).

DROZ J.P, PICO J.L, GHOSN M, KRAMAR A, REY A, OSTRONOFF M, BAUME D, A phase II trial of early intensive chemotherapy with autologus bone marrow transplantation in the treatment of poor prognosis non seminomatous germ cell tumors. Bulletin du Cancer 1992, 79: 497 - 507. (Original).

ROUGIER Ph, AMMARGUELLAT H, GHOSN M, PIOT G, BENHAMED M, TIGAUD J.M, LAPLAIGE Ph, THEODORE C, KAC J, GOLDBERG J, CARDE P, DROZ J.P, Phase II trial of 7-Day continuous 5-Fluorouracil Infusion in the treatment of advanced colorectal carcinoma. Oncology 1992, 49 (1): 35 – 9. (Original).

GHOSN M, TANNOUS R, GEDEON E, The cancer registry at the Hotel Dieu de France Hospital. Lebanese Medical Journal1992, 40 (1): 4 – 10. (Original).

1991

DROZ J.P, PICO J.L, GHOSN M, GOUYETTE A, BAUME D, PIOT G, OSTRONOFF M, THEODORE C, BEAUJEAN F, HAYAT M, Long-term survivors after salvage high dose chemotherapy with bone marrow rescue in refractory germ cell cancer. European Journal of Cancer 1991, 27 (7): 831 – 5. (Original).

GHOSN M, GHAYAD E, BIAGINI J, ABI GERGES D, Métastaseshypothalamo-hyopophysaireetgastrique d’un cancer du sein. Cascliniqueet revue de la littérature. . Bulletin du Cancer 1991, 78 : 1071 – 3. (Case/review).

1990

GHOSN M, HA M.C, PIETRI F, GARCIN C, THEODORE C, DROZ J.P., Trial of premedication with lorazepam for the prevention of emetic effects of cisplatin.. Bulletin du Cancer 1990, 77 (7): 695-6. (Original).

RIBRAG V, DROZ J.P, BOULEUC C, THEODORE C, GHOSN, PICO J.L, AZAB J.L, OSTRONOFF M, HAYAT M, Salvage chemotherapy of non-seminotamous germ cell tumors. Phase II trial of a combination of etoposide, ifosfamide and high-dose cisplatin.. PresseMédicale 1990, 19 (27): 1263-6. (Original).

DROZ J.P, SCHLUMBERGER M, ROUGIER Ph, GHOSN M, GARDET P, PARMENTIER C, Chemotherapy in metastatic nonanaplastic thyroid cancer: experience at the InstitutGustaveRoussy. Tumori 1990, 76 (5): 480 – 3. (Original).

CULINE S, GHOSN M, DROZ J.P, Inappropriate Anti-Diuretic hormone secretion induced by Ifosfamide. European Journal of Cancer 1990, 26 (8): 922. (Original).

GUIMARAES J.L, GHOSN M, OSTRONOFF M, AZAB M, THEODORE C, DROZ J.P, Phase II trial of Methyl-Gag and Melphalan in metastatic renal cell carcinoma. Cancer Investigation 1990, 8 (6): 623 – 4. (Original).

DROZ J.P, RUFFIE P, PIOT G, GHOSN M, GAILLAUD J.M, ELIAS D, PERRIN J.L, LEVASSEUR Ph, Sarcoidosis and testicular germ cell tumor: Case report. Scandinavian Journal of Urology and Nephrology 1990, 24: 171 – 3. (Case report).

DROZ JP, AZAB MB, THEODORE C, GHOSN M, OSTRONOFF M, BOUTAN-LAROZE A, COURT BH, PERRIN JL, TRAVAGLI JP, WIBAULT P., Phase II trial of preoperative and postoperative cisplatin, methotrexate and vinblastine in infiltrating bladder cancer: a three year experience. Progress in Clinical and Biological Research 1990, 353: 137-42. (Original).

MAHJOUBI M, AZAB M, GHOSN M, THEODORE C, DROZ J.P, Phase II trial of Ifosfamide in hormone refractory metastatic cancer of the prostate. Cancer Investigation 1990, 8 (5): 477 – 81. (Original).

RIBRAG V, GHNASSIA C, THEODORE C, GHOSN M, PIOT G, BEUTRON D, CUKIER J, DROZ J.P, Chemotherapy in advanced transitional cell carcinoma of the urinary tract. Phase II trial of a combination of doxorubicin and cisplatin. Journal d’Urologie 1990, 96 (7): 373-4. (Original).

LUPERA H, DROZ J.P, CULINE C, PERKIN J.L, COURT B.H, GHOSN M, HAYAT M, Cancer of the bladder after treatment with cyclophosphamide. A propos of a case and a review of the literature. Journal d’Urologie 1990, 96 (1): 48 – 52. (Review).

GHOSN M, HA M.C, PIETRI F, GARCIN C, THEODORE C, DROZ J.P, Lorazepam premedication for prevention of induced cisplatin nausea. Bulletin du Cancer 1990, 77 (7): 695-6. (Original).

DROZ J.P, PICO P.L, GHOSN M, OSTRONOFF M, AZAB M, THEODORE C, HAYAT M, Chemotherapeutic intensification in germ cell tumors. Bulletin du Cancer 1990, 77 (4): 349 – 54. (Original).

BAUME D, PICO J.L, DROZ J.P, OSTRONOFF M, AZAB M, GILLES E, GHOSN M, SALLOUM GOUYETTE A, BEAUJEAN F, CABANES P.A, BENHAMOU E, HAYAT M, Intêrét de la chimiothérapie à haute dose suivied’autogreffe de moelleosseusedans les tumeursgerminales non séminomateuses de mauvaispronostic :Résultats de l’associationCisplatinum, Etoposide et Cyclophosphamide (protocole PEC). Bulletin du Cancer 1990, 77: 169 – 80. (Original).

1989

DROZ JP, RIBRAG V, GHOSN M, GUIMARES J, THEODORE C, AZAB M, OSTRONOFF M, MAHJOUBI M, MORAN A, PICO J et al, Phase II trial with etoposide (VP16) plus ifosfamide plus high-dose cisplatin (VIhP regimen) in refractory germ cell tumors. Progress in Clinical and Biological Research 1989, 303: 739-47. (Original).

LUPERA H, THEODORE C, GHOSN M, COURT B.H, WIBAULT P, DROZ J.P, Phase II trial of combination chemotherapy with Dacarbazine, Cyclophosphamide, Cisplatin, Doxirubicin and Vindestin (DECAV) in advanced renal cell cancer. Urology 1989, 34 (5): 281 – 3. (Original) .

CULINE S, AZAB M, PIETRI F, GHOSN M, BEN AMOR B, LUPERA H, THEODORE C, RENAUX J, DROZ J.P, Essai phase III comparantl’activité anti-émétique du tetracosactide à la dexaméthasoneemployés en association avec le métoclopramide, la diphenhydramine et le clorazépate au cours de chimiothérapiescomportant du cisplatine. Bulletin du Cancer 1989, 76 (6): 583 - 9. (Original).

ROUGIER Ph, LASSER P, ELIAS D, GHOSN M, DUCREUX M, LUMBROSO J, SIDIBE S, DROZ J.P, Intra arterial hepatic chemotherapy for metastatic liver from colo-rectal carcinoma origin. Selective Cancer Therapeutics 1989, 5 (1): 47-54.(Original).

SALLOUM E, PICO J.L, HERAIT P, BAYLE C, GHOSN M, MORAN A, FRIEDMAN S, HAYAT M, Very late recurrence of childhood acute lymphoblastic leukemia treated with chemoimmunotherapy. Medical and Pediatric Oncology 1989, 17 (2): 155 – 8. (Original).

1988

GHOSN M, DROZ J.P, Ifosfamide in tumor therapy: Contributions to Oncology. Bulletin du Cancer 1988, 75: 831 – 6. (Original).

PIOT G, DROZ J.P, THEODORE C, GHOSN M, ROUESSE J, AMIEL J.L, Phase II trial with high dose elliptinuim acetate in metastatic renal cell carcinoma. Oncology 1988, 45 (5): 371 – 2. (Original).

ROUGIER Ph, GHOSN M, PIOT G, BENHAMED M, LAPLAIGE Ph, THEODORE C, KAC C, CARDE P, DROZ J.P, Chimiothérapie continue par 5 FU systémique: Résultatscliniquesdans les adénocarcinomescolo-rectaux. Cancer Communication 1988, 2 (5), (suppl): 21 – 3. (Original).

DE FORGES A, REY A, KLINK M, GHOSN M, KRAMAR A, DROZ J.P, Prognostic factors of adult metastatic renal carcinoma: a multivariate analysis. Seminars in Surgical Oncology 1988, 4 (3): 146 – 54 (Original).

DROZ J.P, THEODORE C, GHOSN M, LUPERA H, PIOT G, DE FORGES A, KLINK M, ROUESSE J, AMIEL J.L, Twelve year experience with chemotherapy in adult metastatic renal cell carcinoma at the InstitutGustaveRoussy. Seminars in Surgical Oncology 1988, 4 (2): 97 – 9 (Original).

GHOSN M, DROZ J.P, THEODORE C, PICO J.L, BAUME D, SPIELMANN M, OSTRONOFF M, MORAN A, SALLOUM E, KRAMAR A, HAYAT M, Salvage chemotherapy in refractory germ cell tumors with etoposide (VP-16) plus Ifosfamide plus high dose Cisplatinum. A VIhP regimen. Cancer 1988, 62 (1): 24 - 7. (Original).

DROZ J.P, KRAMAR A, GHOSN M, PIOT G, REY A, THEODORE C, WIBAULT P, COURT B.H, PERRIN J.L, TRAVAGALI J.P, BELLET D, CAILLAUD J.M, PICO J.L, HAYAT M, Prognostic factors in advanced non seminomatous testicular cancer: a multivariate logistic regression analysis. Cancer 1988, 62 (3): 564 – 8. (Original).

GHOSN M, CARDE P, LECLERQ B, FLAMANT F, FRIEDMAN S, HAYAT M, Ifosfamide/Mesna related encephalopathy: a case report with a possible role of phenobarbital in enhancing neurotoxicity. Bulletin du Cancer 1988, 75 (4): 391 – 2. (Letter to the Editor).

TALEB N, GEAHCHAN N, GHOSN M, BRIHI E, SACR P, Vulvar pruritis after high dose Dexamethasone. European Journal of Cancer 1988, 24 (3): 495. (Letter to the Editor).

1987

ROUGIER P, LASSER P, DROZ J.P, ELIAS D, GHOSN M, DUCREUX M, LUMBROSO J, SIDIBE S, ChimiothérapieLocorégionale des métastaseshépatiques du Cancer colo-rectal. Annals of Gastroenterology Hepatology 1987, 23 (6): 315 – 9. (Original).

DE FORGES A, DROZ J.P, GHOSN M, THEODORE C, Phase II trial of Ifosfamide /Mesna in metastatic adult renal carcinoma. Cancer treatment reports 1987, 71 (11): 1103. (Original).

SALLOUM E, FLAMANT F, GHOSN M, TALEB N, AKATCHARIAN C, Irreversible encephalopathy with Ifosfamide/Mesna. Journal of Clinical Oncology 1987, 5 (8): 1303 – 4.(Letter to the Editor).

GHOSN M, DROZ J.P, Compterendu du Congrès de l’American Society of Clinical Oncology. (Tumeursurologiques, Atlanta, 17-19 may 1987). Journal d’Urologie (Paris) 1987, N° 9-10, p 565 – 9. (Meeting report).